[PRACTICE NOTE] Refocusing Leadership DNA in Pharma
The beliefs a company truly values and the behaviors it exhibits are largely a function of the leadership tone set at the highest levels. That holds in every industry, and it holds with unusual force in pharma, where the distance between a scientific promise and a patient outcome runs through dozens of handoffs. Leaders rarely touch those handoffs directly. What they do touch is the question of whether anyone is expected to own the whole of them.
Pharma has no shortage of leaders who believe in the customer. The belief tends to live in sentiment rather than in structure, which is why it rarely survives a quarter that comes in light. Commitment that is built into how leaders are evaluated, how capital is allocated and what the board reviews behaves differently.
The gap between those two conditions shows up in how differently leaders and customers describe the same engagement. Deloitte 2025 research found only 28 percent of HCPs believe pharma's engagement strategies meet their needs, against 82 percent of life sciences executives who say they are satisfied with those same strategies. A spread of that size may not be an information problem. Executives are reading accurate reports about activity while providers are describing their experience of the system.
Leadership acumen is not a charismatic gift or a title
Exceptional leadership of this kind is not an innate trait that only a few charismatic leaders possess, nor does it belong to anyone holding a Chief Customer Officer or Chief Experience Officer title. What leaders at every level need is a belief that exceptional customer experiences can change the basis of competition in their favor. That belief can be learned, and it can be tested against how a leader spends time, attention and money.
In the book this work sits in the first of four layers, Leadership DNA, ahead of Organizational, Operational and Commercial DNA. The sequence matters more than the taxonomy. Leadership DNA is the layer that determines whether a commitment to the customer survives contact with a quarterly target. Without it the other three layers remain optional. That is the quiet reason so many pharma customer experience programs fail while every initiative inside them performs as designed.
Reframe the theory of the firm around relationship value
The theory of the firm was developed by economists to explain why firms exist and why they organize themselves as they do. Most early conceptions emphasized efficiency, minimized transaction costs and other mass production era factors. Reframing it means recalibrating value drivers and growth vectors around customer relationship value, goodwill, reciprocity and trust. In pharma this is the move from a firm that exists to discover and promote medicines. The reframed firm exists to see those medicines reach and stay with patients.
A firm organized around discovery and promotion funds reach, frequency and share of voice. A firm organized around reaching and staying with patients funds the removal of friction between a decision and a therapy. Both can be reported as growth, and only one of them accumulates something that compounds.
Treat each customer relationship as a quantifiable asset
"Our customers are our most important asset" is one of the most repeated platitudes in business. Treating it as substance means each customer relationship becomes an intangible but quantifiable unit of value on a virtual balance sheet. That brings visibility to which relationships are appreciating, which are depreciating and which are worth further investment. Some of that accounting may be imperfect, and it remains more honest than treating relationships as free.
In pharma the relationships in question are a prescriber's confidence and a patient's willingness to stay on therapy, and both are routinely spent without being counted. A difficult prior authorization draws down prescriber confidence, and a confusing copay conversation draws down patient willingness. Neither withdrawal appears anywhere, which is why value leakage can run for years without a line item.
Experience-led growth belongs inside corporate strategy
An experience-led growth strategy has to be a subset of corporate strategy rather than something created in a vacuum. It has to name the experiential battlefields the company chooses to compete on beyond its core products. It also has to act as a revenue driver across every stage of the lifecycle. Treating experience as a post purchase concern caps what it can return. Strategies written outside those three conditions often produce activity that is admired internally and invisible commercially.
In pharma that means choosing which of the three paths the company intends to be visibly better at, and funding it. The Path to Prescribe, the Path to Fulfill and the Path to Adhere behave differently and fail differently. Most organizations hold strong opinions about the first and carry almost no stated ambition about the other two. Choosing one of them as a battlefield is a strategy decision rather than a program.
Employees read their leaders for what is acceptable
Modeling customer-centric behaviors has less to do with declarations than with what the organization sees leaders repeat. Three practices carry most of the weight.
A cadence of communications brings the customer perspective into management systems rather than leaving it to an annual offsite. Consistency of intent matters because variable experiences across channels produce customer and employee dissonance in equal measure. The third practice is celebration, so that Customer Excellence is visibly rewarded rather than quietly assumed.
What gets celebrated tells employees where discretionary effort can be safely spent. Being this kind of enterprise also means resisting the temptation to chase fleeting management trends and quick fixes. Enduring value comes from structural change, and structural change rarely photographs well in a town hall.
Empowerment turns autonomy into accountability for customer outcomes
When leaders empower employees they entrust them with autonomy and authority, and in return employees feel trusted and accept accountability for customer outcomes. Two components do most of this work, and the first is prioritization, which means putting the customer and the employee on business review and board agendas.
The second is permission, which means granting the institutional permission employees need to uphold brand promises. In pharma, and in my own experience of commercial organizations, the permission question is sharpest in the field. Colleagues there routinely see what is failing a patient and have no sanctioned route to act on it. Field teams in this position are not underperforming, and the structure around them is not built to receive what they know.
Governance is where the commitment becomes verifiable
Governance is the proof that the commitment is real, and it escalates in three steps. The first is to incorporate Customer Excellence into strategic transactions, where diligence usually ignores it entirely. The second is to form a dedicated board committee or sub-committee tasked with championing customer centricity and holding the organization accountable. The third is to integrate customer outcome metrics and narratives into quarterly filings, annual reports and other disclosures.
Each step raises the cost of walking the commitment back, which is largely the point of governance. I have watched organizations complete the first step and treat it as the whole program. The step that changes behavior most reliably is a smaller one. Strategic customer experience metrics belong in executive leadership evaluations, so that leaders are held accountable rather than merely supportive.
Pharma's defensible numbers conceal the gap nobody owns
Every function in a commercial organization can defend its own number, and each defense is accurate. Marketing can defend awareness and recall. Sales can defend reach and frequency. Medical can defend scientific exchange, and market access can defend coverage secured. Patient services can defend enrolled patients supported to service levels.
I have sat through reviews where each of those numbers was sound and the patient's path through them was never discussed. Every leader in the room can defend a number while providers and patients continue to experience delay and abandonment. No individual in that room is failing. The structure is not built to surface the thing none of them owns, which is whether earned value becomes realized therapy.
That question has no functional home, so it often gets treated as a measurement problem rather than an accountability one. A billion dollars of earned value becomes roughly seven hundred million after prescriptions that are never filled. It falls again after early discontinuation, and settles close to four hundred and fifty million in realized value after long term adherence erosion. No competitor takes the difference, and the Realization Rate is the number that would make the loss visible.
Leadership DNA creates the conditions for the layer beneath it to function. Organizational DNA is the next layer, where structure, roles and incentives either carry the commitment or quietly absorb it. Operational DNA and Commercial DNA follow it in turn, and leaders who skip the first layer tend to buy capability they cannot govern.
Heroics are a subsidy the enterprise never books
Capable people prevent most of these gaps from becoming visible failures. Someone calls a payer a second time, reworks a form, or stays late to keep a patient from falling out of a program. Leadership usually sees the resolution without seeing the effort required to produce it, because the system looks like it works when somebody makes it work.
Heroics are a subsidy. They are paid by employees, they go unrecorded in reporting, and they run out when the people paying them leave or tire. The alternative is an enterprise that is structurally predisposed to help, where the right outcome arrives as the default rather than the achievement. Leadership DNA is what decides which of those two enterprises a company becomes.
Key Takeaways
- Leadership tone, rather than title or temperament, largely determines whether a customer commitment survives a quarter that comes in light.
- Reframing the theory of the firm means funding the distance between a prescription earned and a therapy sustained.
- Prescriber confidence and patient willingness behave like assets that appreciate or depreciate, and most organizations spend them without counting them.
- An experience-led growth strategy only works when it names a battlefield and receives funding inside corporate strategy.
- Governance makes the commitment verifiable, and executive evaluations are where accountability stops being sponsorship.
- Heroics can hold a broken path together for some time, and they remain a subsidy rather than a capability.
Diagnostic Questions to Consider
- Name the experiential battlefield your company has chosen to compete on beyond its molecules.
- Identify where prescriber confidence and patient willingness appear in any document the board reviews.
- Describe the sanctioned route a field colleague uses when they see something failing a patient.
- State which executive evaluation carries a customer outcome metric with real weight attached to it.
- Estimate how much of current performance may depend on effort that nobody reports.
Closing Reflection
The move described here is modest in language and large in consequence. Leaders do not have to become experience designers, and they do have to become the principal advocates for customers inside their own management systems. That advocacy is most useful when it is repetitive, unglamorous and attached to money. A belief expressed once a year at an offsite can be sincere and still change nothing.
Pharma has earned the right to be judged on more than molecules, and the layer that would let it be judged that way is largely unbuilt. The three legs of the value proposition are product, brand and experience, and pharma built two of them well. Leadership DNA is where the third leg gets its budget, its owner and its place on an agenda.
I have come to see this layer as the least technical and the most difficult of the four. Structure can be redrawn, processes can be rebuilt and commercial models can be redesigned, often within a single planning cycle. Changing what leaders reliably ask about takes longer, because it asks them to be measured on something they used to sponsor. The organizations willing to make that trade tend to stop needing heroes.
About the Author
Wayne Simmons is the founder of The Customer Excellence AGENCY and the author of The Customer Excellence Enterprise (Wiley, 2024). He is founding faculty of the MS in Customer Experience Management at Michigan State University's Broad College of Business. He led global customer excellence in Pfizer's first Chief Marketing Organization and in Bayer's Customer Powerhouse.
The Customer Excellence Agency: Advancing the Pursuit of Excellence in Service of Science.







